Dilution is not the solution: acute hemolytic transfusion reaction after ABO-incompatible pooled platelet transfusion

Transfusion Support for ABO-Incompatible Progenitor Cell Transplantation.

ABO-incompatible transplants comprise up to 50% of allogeneic progenitor cell transplants. Major, minor and bidirectional ABO-incompatible transplants each have unique complications that can occur, including hemolysis at the time of progenitor cell infusion, hemolysis during donor engraftment, passenger lymphocyte syndrome, delayed red blood cell engraftment, and pure red cell aplasia. Appropri...

Rare antibody-associated hemolytic transfusion reaction and transfusion-related acute lung injury: a case report

BACKGROUND Hemolytic transfusion reactions and transfusion-related acute lung injury (TRALI) are life-threatening complications associated with the transfusion of blood products. Hemorrhage is one of the most common surgical complications and the risk of bleeding is particularly acute in patients with hematologic deficiencies. Management of surgical bleeding can be divided into two phases. The ...

Hemolytic transfusion reaction due to anti-IH.

BACKGROUND Anti-IH is usually a clinically insignificant antibody that may complicate a serologic workup. However, it can occasionally cause hemolysis. We report a rare case of acute hemolysis caused by anti-IH. CASE REPORT A 60-year-old man with a long history of chronic myelomonocytic leukemia and anemia, blood group A, D+ was found to have an unidentified antibody on serologic workup. He r...

Hemolytic transfusion reaction due to anti-A.

Erythropoiesis after exchange transfusion in hemolytic anemia.

I HE CONTROL of red cell productiomi is undoubtedly geared toward maintaining the red cell mass at a functionally optimal size. Since the primary function of the red cell mass is to transport oxygen to the tissues, it is generally assumed that the control is triggered by the tissue tension of oxygen. Recent studies indicate that the oxygen tension in one target area, the kidney, is inversely pr...